Friday, May 12, 2017

ABO blood types



Today in science we determined my ABO and Rh Blood type. 

For all of you non-nurses out there here is a little info on what this alphabetical gibberish means.


Red blood cells are similar but differ in that they have either have or don't have several antigens (proteins), and are classified by the presence or lack of three different antigens. Antigens are proteins that can be found on the outside of cells, including your red blood cells. Your blood contains antibodies (more proteins) that peruse the cells in your blood. When the antibody "sees" a cell with antigens that don't match the antibody signals for a lot of other antibodies to be produced. These antibodies are slightly different: they swarm around the foreign antibodies that didn't match the original antibody. This signals for the white blood cells to attack the pathogen. This process is part of both the innate and acquired immune system.  So, if you get a blood transfusion with blood cells with antigens that aren't the same as the ones on your blood cells the process will be carried out on those blood cells. This causes many issues. But, there is hope: the blood transfusion does not have to be from a donor with a  perfect blood type match because as long as the blood does not have antigens that your blood does not have, your antibody won't recognize it as different and therefore won't attack the foreign blood. 

according to redcrossblood.org:


  • Group A – has only the A antigen on red cells (and B antibody in the plasma)
  • Group B – has only the B antigen on red cells (and A antibody in the plasma)
  • Group AB – has both A and B antigens on red cells (but neither A nor B antibody in the plasma)
  • Group O – has neither A nor B antigens on red cells (but both A and B antibody are in the plasma)

Trial
Reaction With A (Y/N)
Reaction With B (Y/N)
Reaction With Rh (Y/N)
Blood type
Isaac
N
N
Y
O+

Questions

  • The blood types in the Introduction are for red blood cells. There are other cell types in your blood though. What are the other cell types and do they have the same blood typing systems?
Neutrophils digest bacteria Monocytes become macrophages Lymphocytes consist of B cells and T cells Platelets help blood to clot
  • platelets
    • https://www.ncbi.nlm.nih.gov/books/NBK2263/
    • https://medlineplus.gov/ency/article/001306.htm
  • What blood type is needed for a transfusion for a Type O positive patient?
    • O positive or negative
  • What would happen if someone was transfused with an incompatible blood type
    • SWARM!SWARM!SWARM!SWARM!SWARM!SWARM!SWARM!SWARM!SWARM! 
    • according to medlineplus.gov the symptoms of an ABO incompatible transfusion reaction include
      • Back pain
      • Blood in urine
      • Chills
      • Feeling of "impending doom"
      • Fever
      • Yellow skin and whites of the eyes (jaundice)



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